abstract：BACKGROUND:The increasing availability of whole genome sequences allows the gene or protein content of different organisms to be compared, leading to burgeoning interest in the relatively new subfield of pan-genomics. However, while several studies have analyzed protein content relationships in specific groups of bacte...

journal_title：BMC microbiology

authors： Trost B,Haakensen M,Pittet V,Ziola B,Kusalik A

更新日期：2010-10-13 00:00:00

abstract：BACKGROUND:Bordetella dermonecrotic toxin (DNT) causes the turbinate atrophy in swine atrophic rhinitis, caused by a Bordetella bronchiseptica infection of pigs, by inhibiting osteoblastic differentiation. The toxin is not actively secreted from the bacteria, and is presumed to be present in only small amounts in infec...

journal_title：BMC microbiology

authors： Fukui-Miyazaki A,Kamitani S,Miyake M,Horiguchi Y

更新日期：2010-09-25 00:00:00

abstract：BACKGROUND:Cysteine has a crucial role in cellular physiology and its synthesis is tightly controlled due to its reactivity. However, little is known about the sulfur metabolism and its regulation in clostridia compared with other firmicutes. In Clostridium perfringens, the two-component system, VirR/VirS, controls the...

journal_title：BMC microbiology

authors： André G,Haudecoeur E,Monot M,Ohtani K,Shimizu T,Dupuy B,Martin-Verstraete I

更新日期：2010-09-07 00:00:00

abstract：BACKGROUND:Salmonella enterica is a facultative intracellular pathogen that replicates within a membrane-bound compartment termed Salmonella containing vacuole (SCV). The biogenesis of SCV requires Salmonella type III protein secretion/translocation system and their effector proteins which are translocated into host ce...

journal_title：BMC microbiology

authors： Wang X,Li D,Qu D,Zhou D

更新日期：2010-08-26 00:00:00

abstract：BACKGROUND:In the present work, we describe a group of anomalous dose-response (DR) profiles and develop a dynamic model that is able to explain them. Responses were obtained from conventional assays of three antimicrobial agents (nisin, pediocin and phenol) against two microorganisms (Carnobacterium piscicola and Leuc...

journal_title：BMC microbiology

authors： Murado MA,Vázquez JA

更新日期：2010-08-19 00:00:00

abstract：BACKGROUND:Alpha (alpha)-hemolysin is a pore forming cytolysin and serves as a virulence factor in intestinal and extraintestinal pathogenic strains of E. coli. It was suggested that the genes encoding alpha-hemolysin (hlyCABD) which can be found on the chromosome and plasmid, were acquired through horizontal gene tran...

journal_title：BMC microbiology

authors： Burgos Y,Beutin L

更新日期：2010-07-19 00:00:00

abstract：BACKGROUND:Epitope tagging is a powerful strategy to study the function of proteins. Although tools for C-terminal protein tagging in the ciliated protozoan Tetrahymena thermophila have been developed, N-terminal protein tagging in this organism is still technically demanding. RESULTS:In this study, we have establishe...

journal_title：BMC microbiology

authors： Busch CJ,Vogt A,Mochizuki K

更新日期：2010-07-13 00:00:00

abstract：BACKGROUND:Biofilms are ubiquitous. For instance, the majority of medical infections are thought to involve biofilms. However even after decades of investigation, the in vivo efficacy of many antimicrobial strategies is still debated suggesting there is a need for better understanding of biofilm antimicrobial tolerance...

journal_title：BMC microbiology

authors： Zuroff TR,Bernstein H,Lloyd-Randolfi J,Jimenez-Taracido L,Stewart PS,Carlson RP

更新日期：2010-07-07 00:00:00

abstract：BACKGROUND:Klebsiella pneumoniae is an important gram-negative opportunistic pathogen causing primarily urinary tract infections, respiratory infections, and bacteraemia. The ability of bacteria to form biofilms on medical devices, e.g. catheters, has a major role in development of many nosocomial infections. Most clin...

journal_title：BMC microbiology

authors： Schroll C,Barken KB,Krogfelt KA,Struve C

更新日期：2010-06-23 00:00:00

abstract：BACKGROUND:Photorhabdus are Gram negative bacteria that are pathogenic to insect larvae whilst also having a mutualistic interaction with nematodes from the family Heterorhabditis. Iron is an essential nutrient and bacteria have different mechanisms for obtaining both the ferrous (Fe2+) and ferric (Fe3+) forms of this ...

journal_title：BMC microbiology

authors： Watson RJ,Millichap P,Joyce SA,Reynolds S,Clarke DJ

更新日期：2010-06-22 00:00:00

abstract：BACKGROUND:Quorum sensing is a communication system that regulates gene expression in response to population density and often regulates virulence determinants. Deletion of the luxR homologue vjbR highly attenuates intracellular survival of Brucella melitensis and has been interpreted to be an indication of a role for ...

journal_title：BMC microbiology

authors： Weeks JN,Galindo CL,Drake KL,Adams GL,Garner HR,Ficht TA

更新日期：2010-06-08 00:00:00

abstract：BACKGROUND:Escherichia coli strains are commonly found in the gut microflora of warm-blooded animals. These strains can be assigned to one of the four main phylogenetic groups, A, B1, B2 and D, which can be divided into seven subgroups (A0, A1, B1, B22, B23, D1 and D2), according to the combination of the three genetic...

journal_title：BMC microbiology

authors： Carlos C,Pires MM,Stoppe NC,Hachich EM,Sato MI,Gomes TA,Amaral LA,Ottoboni LM

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:The Beijing lineage of Mycobacterium tuberculosis is causing concern due to its global distribution and its involvement in severe outbreaks. Studies focused on this lineage are mainly restricted to geographical settings where its prevalence is high, whereas those in other areas are scarce. In this study, we ...

journal_title：BMC microbiology

authors： Alonso M,Alonso Rodriguez N,Garzelli C,Martínez Lirola M,Herranz M,Samper S,Ruiz Serrano MJ,Bouza E,García de Viedma D

更新日期：2010-05-25 00:00:00

abstract：BACKGROUND:Poorly understood but highly diverse microbial communities exist within anoxic and oxygen-depleted marine sediments. These communities often harbour single-celled eukaryotes that form symbiotic associations with different prokaryotes. During low tides in South-western British Columbia, Canada, vast areas of ...

journal_title：BMC microbiology

authors： Breglia SA,Yubuki N,Hoppenrath M,Leander BS

更新日期：2010-05-19 00:00:00

abstract：BACKGROUND:Photorhabdus are Gram-negative nematode-symbiotic and insect-pathogenic bacteria. The species Photorhabdus asymbiotica is able to infect humans as well as insects. We investigated the secreted proteome of a clinical isolate of P. asymbiotica at different temperatures in order to identify proteins relevant to...

journal_title：BMC microbiology

authors： Jones RT,Sanchez-Contreras M,Vlisidou I,Amos MR,Yang G,Muñoz-Berbel X,Upadhyay A,Potter UJ,Joyce SA,Ciche TA,Jenkins AT,Bagby S,Ffrench-Constant RH,Waterfield NR

更新日期：2010-05-12 00:00:00

abstract：BACKGROUND:The RNA interference (RNAi) pathway acts as an innate antiviral immune response in Aedes aegypti, modulating arbovirus infection of mosquitoes. Sindbis virus (SINV; family: Togaviridae, genus: Alphavirus) is an arbovirus that infects Ae. aegypti in the laboratory. SINV strain TR339 encounters a midgut escape...

journal_title：BMC microbiology

authors： Khoo CC,Piper J,Sanchez-Vargas I,Olson KE,Franz AW

更新日期：2010-04-28 00:00:00

abstract：BACKGROUND:The mce operons play an important role in the entry of M. tuberculosis into macrophages and non-phagocytic cells. Their non-redundant function as well as complex regulation is implied by the phenotype of mce mutants. Recently, mce1 operon was found to extend over 13 genes, fadD5 (Rv0166) being the first gene...

journal_title：BMC microbiology

authors： Joon M,Bhatia S,Pasricha R,Bose M,Brahmachari V

更新日期：2010-04-27 00:00:00

abstract：BACKGROUND:The gut comprises an essential barrier that protects both invertebrate and vertebrate animals from invasion by microorganisms. Disruption of the balanced relationship between indigenous gut microbiota and their host can result in gut bacteria eliciting host responses similar to those caused by invasive patho...

journal_title：BMC microbiology

authors： Broderick NA,Raffa KF,Handelsman J

更新日期：2010-04-27 00:00:00

abstract：BACKGROUND:Macrolide antibiotics are commonly administered for bacterial respiratory illnesses. Azithromycin (Az) is especially noted for extremely high intracellular concentrations achieved within macrophages which is far greater than the serum concentration. Clinical strains of Type B Francisella (F.) tularensis have...

journal_title：BMC microbiology

authors： Ahmad S,Hunter L,Qin A,Mann BJ,van Hoek ML

更新日期：2010-04-23 00:00:00

abstract：BACKGROUND:Affecting the core functional microbiome, peculiar high level taxonomic unbalances of the human intestinal microbiota have been recently associated with specific diseases, such as obesity, inflammatory bowel diseases, and intestinal inflammation. RESULTS:In order to specifically monitor microbiota unbalance...

journal_title：BMC microbiology

authors： Candela M,Consolandi C,Severgnini M,Biagi E,Castiglioni B,Vitali B,De Bellis G,Brigidi P

更新日期：2010-04-19 00:00:00

abstract：BACKGROUND:Invasive aspergillosis (IA) is a major cause of infectious morbidity and mortality in immune compromised patients. Studies on the pathogenesis of IA have been limited by the difficulty to monitor disease progression in real-time. For real-time monitoring of the infection, we recently engineered a bioluminesc...

journal_title：BMC microbiology

authors： Ibrahim-Granet O,Jouvion G,Hohl TM,Droin-Bergère S,Philippart F,Kim OY,Adib-Conquy M,Schwendener R,Cavaillon JM,Brock M

更新日期：2010-04-08 00:00:00

abstract：BACKGROUND:The functions of proteins are strongly related to their localization in cell compartments (for example the cytoplasm or membranes) but the experimental determination of the sub-cellular localization of proteomes is laborious and expensive. A fast and low-cost alternative approach is in silico prediction, bas...

journal_title：BMC microbiology

authors： Goudenège D,Avner S,Lucchetti-Miganeh C,Barloy-Hubler F

更新日期：2010-03-23 00:00:00

abstract：BACKGROUND:Understanding mollicutes is challenging due to their variety and relationship with host cells. Invasion has explained issues related to their opportunistic role. Few studies have been done on the Ureaplasma diversum mollicute, which is detected in healthy or diseased bovine. The invasion in Hep-2 cells of fo...

journal_title：BMC microbiology

authors： Marques LM,Ueno PM,Buzinhani M,Cortez BA,Neto RL,Yamaguti M,Oliveira RC,Guimarães AM,Monezi TA,Braga AC Jr,Machado-Santelli GM,Timenetsky J

更新日期：2010-03-17 00:00:00

abstract：BACKGROUND:Nitrosomonas europaea is a widely studied chemolithoautotrophic ammonia oxidizing bacterium. While significant work exists on the ammonia oxidation pathway of N. europaea, its responses to factors such as dissolved oxygen limitation or sufficiency or exposure to high nitrite concentrations, particularly at t...

journal_title：BMC microbiology

authors： Yu R,Chandran K

更新日期：2010-03-04 00:00:00

abstract：BACKGROUND:It is known that insects and crustaceans can carry simultaneous, active infections of two or more viruses without showing signs of disease, but it was not clear whether co-infecting viruses occupied the same cells or different cells in common target tissues. Our previous work showed that successive challenge...

journal_title：BMC microbiology

authors： Kanthong N,Khemnu N,Pattanakitsakul SN,Malasit P,Flegel TW

更新日期：2010-01-20 00:00:00

abstract：BACKGROUND:Vibrio cholerae is the causative agent of cholera. Extensive studies reveal that complicated regulatory cascades regulate expression of virulence genes, the products of which are required for V. cholerae to colonize and cause disease. In this study, we investigated the expression of the key virulence regulat...

journal_title：BMC microbiology

authors： Xu X,Stern AM,Liu Z,Kan B,Zhu J

更新日期：2010-01-06 00:00:00

abstract：BACKGROUND:Microbial biofilms are known to cause an increasing number of chronic inflammatory and infectious conditions. A classical example is chronic periodontal disease, a condition initiated by the subgingival dental plaque biofilm on gingival epithelial tissues. We describe here a new model that permits the examin...

journal_title：BMC microbiology

authors： Guggenheim B,Gmür R,Galicia JC,Stathopoulou PG,Benakanakere MR,Meier A,Thurnheer T,Kinane DF

更新日期：2009-12-31 00:00:00

abstract：BACKGROUND:Ochrobactrum anthropi is a versatile bacterial species with strains living in very diverse habitats. It is increasingly recognized as opportunistic pathogen in hospitalized patients. The population biology of the species particularly with regard to the characteristics of the human isolates is being investiga...

journal_title：BMC microbiology

authors： Romano S,Aujoulat F,Jumas-Bilak E,Masnou A,Jeannot JL,Falsen E,Marchandin H,Teyssier C

更新日期：2009-12-18 00:00:00

abstract：BACKGROUND:Identification and characterization of intervening sequences (IVSs) within 23S rRNA genes from Campylobacter organisms including atypical campylobacters were carried out using two PCR primer pairs, designed to generate helix 25 and 45 regions. RESULTS:Only C. sputorum biovar sputorum LMG7975 and fecalis LMG...

journal_title：BMC microbiology

authors： Tazumi A,Kakinuma Y,Misawa N,Moore JE,Millar BC,Matsuda M

更新日期：2009-12-11 00:00:00

abstract：BACKGROUND:Staphylococcus aureus methicillin-resistant (MRSA) has been frequently isolated from endotracheal and lung puncture aspirates in malnourished children with pneumonia. In this work we evaluated the susceptibility of undernourished BALB/c mice and its ability to mount a protective immunity against MRSA with em...

journal_title：BMC microbiology

authors： França TG,Ishikawa LL,Zorzella-Pezavento SF,Chiuso-Minicucci F,Guerino CP,da Cunha Mde L,Sartori A

更新日期：2009-11-23 00:00:00

abstract：BACKGROUND:Exposure of cells to environmental stress conditions can lead to the interruption of several intracellular processes, in particular those performed by macromolecular complexes such as the spliceosome. RESULTS:During nucleotide sequencing of cDNA libraries constructed using RNA isolated from B. emersonii cel...

journal_title：BMC microbiology

authors： Georg RC,Stefani RM,Gomes SL

更新日期：2009-10-29 00:00:00

abstract：BACKGROUND:Since bacteria embedded in biofilms are far more difficult to eradicate than planktonic infections, it would be useful to know whether certain Staphylococcus aureus lineages are especially involved in strong biofilm formation. For this reason, in vitro biofilm formation of 228 clinical S. aureus isolates of ...

journal_title：BMC microbiology

authors： Croes S,Deurenberg RH,Boumans ML,Beisser PS,Neef C,Stobberingh EE

更新日期：2009-10-28 00:00:00

abstract：BACKGROUND:Metabolically versatile soil bacteria Burkholderia cepacia complex (Bcc) have emerged as opportunistic pathogens, especially of cystic fibrosis (CF). Previously, we initiated the characterization of the phenylacetic acid (PA) degradation pathway in B. cenocepacia, a member of the Bcc, and demonstrated the ne...

journal_title：BMC microbiology

authors： Hamlin JN,Bloodworth RA,Cardona ST

更新日期：2009-10-18 00:00:00

abstract：BACKGROUND:Bacteriocins are antimicrobial proteins and peptides ribosomally synthesized by some bacteria which can effect both intraspecies and interspecies killing. RESULTS:Moraxella catarrhalis strain E22 containing plasmid pLQ510 was shown to inhibit the growth of M. catarrhalis strain O35E. Two genes (mcbA and mcb...

journal_title：BMC microbiology

authors： Attia AS,Sedillo JL,Hoopman TC,Liu W,Liu L,Brautigam CA,Hansen EJ

更新日期：2009-09-25 00:00:00

abstract：BACKGROUND:Crohn's disease (CD) is a high morbidity chronic inflammatory disorder of unknown aetiology. Adherent-invasive Escherichia coli (AIEC) has been recently implicated in the origin and perpetuation of CD. Because bacterial biofilms in the gut mucosa are suspected to play a role in CD and biofilm formation is a ...

journal_title：BMC microbiology

authors： Martinez-Medina M,Naves P,Blanco J,Aldeguer X,Blanco JE,Blanco M,Ponte C,Soriano F,Darfeuille-Michaud A,Garcia-Gil LJ

更新日期：2009-09-21 00:00:00

abstract：BACKGROUND:The genome of Arthrobacter sp. strain FB24 contains a chromate resistance determinant (CRD), consisting of a cluster of 8 genes located on a 10.6 kb fragment of a 96 kb plasmid. The CRD includes chrA, which encodes a putative chromate efflux protein, and three genes with amino acid similarities to the amino ...

journal_title：BMC microbiology

authors： Henne KL,Nakatsu CH,Thompson DK,Konopka AE

更新日期：2009-09-16 00:00:00

abstract：BACKGROUND:Helicobacter pylori forms biofilms on glass surfaces at the air-liquid interface in in vitro batch cultures; however, biofilms of H. pylori have not been well characterized. In the present study, we analyzed the ability of H. pylori strains to form biofilms and characterized the underlying mechanisms of H. p...

journal_title：BMC microbiology

authors： Yonezawa H,Osaki T,Kurata S,Fukuda M,Kawakami H,Ochiai K,Hanawa T,Kamiya S

更新日期：2009-09-15 00:00:00

abstract：BACKGROUND:Though important in the context of food microbiology and as potential pathogens in immuno-compromised humans, bacterial isolates belonging to the genus Pediococcus are best known for their association with contamination of ethanol fermentation processes (beer, wine, or fuel ethanol). Use of antimicrobial com...

journal_title：BMC microbiology

authors： Haakensen M,Vickers DM,Ziola B

更新日期：2009-09-07 00:00:00

abstract：BACKGROUND:Pectobacterium carotovorum subsp. carotovorum is a phytopathogenic enterobacterium responsible for soft rot, a disease characterized by extensive maceration of the affected plant tissue. This species also produces two or more antibacterial substances called bacteriocins, which enhance its competitiveness aga...

journal_title：BMC microbiology

authors： Chan YC,Wu HP,Chuang DY

更新日期：2009-08-27 00:00:00

abstract：BACKGROUND:L-arabitol dehydrogenase (LAD) and xylitol dehydrogenase (XDH) are involved in the degradation of L-arabinose and D-xylose, which are among the most abundant monosaccharides on earth. Previous data demonstrated that LAD and XDH not only differ in the activity on their biological substrate, but also that only...

journal_title：BMC microbiology

authors： Rutten L,Ribot C,Trejo-Aguilar B,Wösten HA,de Vries RP

更新日期：2009-08-12 00:00:00